William Howard Stein

“The story of the determination of the chemical structure of an enzyme is the story of the extension of the classical methods of organic chemistry to a new frontier of size.”

“We wanted to have a method for the quantitative determination of amino acids that would be more accurate and more rapid than the microbiological methods then available.”

“The success of our enterprise was a tribute to the power of the chromatographic method of analysis.”

“Our interest in the chemistry of proteins, and in particular of enzymes, was stimulated by the late Max Bergmann, who was our mentor.”

“The elucidation of the sequence of the 124 amino acid residues in the chain of bovine pancreatic ribonuclease A has been a cooperative venture, as is so much of scientific research today.”